• Xiao-Ou Zhang

    Xiao-Ou Zhang (PI)

    1239 Siping Road, Shanghai 200092

    Xiao-Ou earned a B.E. in Biological Engineering from Huazhong Agricultural University and a B.S. in Computer Science from Huazhong University of Science and Technology in 2011. He then received his Ph.D. in Computational Biology from the CAS-MPG Partner Institute (PICB), Shanghai Institutes for Biological Sciences (SIBS), Chinese Academy of Sciences (CAS) for Computational Biology in 2016. During his Ph.D. period, he primarily focused on studying the biogenesis and processing mechanisms of long noncoding RNAs with unique structures under the advisement of Prof. Li Yang and Prof. Ling-Ling Chen. He joined the lab of Prof. Zhiping Weng at UMass Chan Medical School as a postdoctoral fellow in 2016, where he developed computational methods to study the functions of repetitive sequences in gene regulation. In 2020, he joined the School of Life Sciences and Technology at Tongji University as a professor and a group leader. His research focuses on developing computational algorithms and conducting big data mining on high-throughput data to investigate gene regulation driven by noncoding sequences.

  • Zhongren Hu

    Zhongren Hu

    e-mail: 2011399@tongji.edu.cn

    Zhongren earned a B.S. in Bioinformatics from Tongji University in 2020 and joined Prof. Xiao-Ou Zhang's lab as a doctoral student in the same year. His research focuses on developing computational methods for detecting transposition events based on long-read sequencing.

  • Bo Xu

    Bo Xu

    e-mail: 1194189468@qq.com

    2016-2020 | Bachelor of Bioinformatics, Tongji University, 2020-present | PhD candidate of Biology, expected 2026, Tongji University. He is focused on profiling transposon insertion in human and fly, and studying the piRNA cluster conservation in mammal's evolution. The final aim is answering how piRNA clusters function in silencing transposon insertion and regulating gene expression.

  • Hanxi Shi

    Hanxi Shi

    e-mail: 2111266@tongji.edu.cn

    Hanxi earned her B.S. in Biology from Tongji University in 2021 and subsequently joined Professor Zhang’s lab to pursue her Ph.D. studies. Her research primarily focuses on investigating the intricate mechanisms underlying the involvement of transposable elements (TEs) in the regulation of gene expression.

  • Ruofan Huang

    Ruofan Huang

    e-mail: ruofanhuang@tongji.edu.cn

    Ruofan obtained a B.E. in Biological Engineering from Beijing University of Chemical and Technology in 2021. She then embarked on her Ph.D. journey under the guidance of Professor Zhang at Tongji University. During her Ph.D. period, she primarily focuses on studying the biogenesis, processing mechanisms, and gene regulation of small noncoding RNAs. Her research, in particular, contributes to advancing the understanding of non-coding sequences and their relevance in human health and disease therapeutics.

  • Xiaobing Gu

    Xiaobing Gu

    e-mail: 2131421@tongji.edu.cn

    Gu Xiaobing obtained a Bachelor’s degree in Bioengineering from East China University of Science and Technology in 2021, and subsequently joined Professor Zhang’s laboratory for her Master’s degree studies. She is currently focused on systematic exploration and evolutionary research of transposon-derived promoters, as well as the establishment of a database.

  • Mingdong Wang

    Mingdong Wang

    e-mail: 2231482@tongji.edu.cn

    I studied bioinformatics in Tongji University as an undergraduate and joined this lab after graduation. I am currently pursuing my master's degree at Tongji University under the supervision of Prof. Xiao-Ou Zhang. Currently I am studying the biological role of enhancers. I hope I can be successful in the near future.

  • Lingfeng Xu

    Lingfeng Xu

    e-mail: 2311465@tongji.edu.cn

    I studied bioinformatics as an undergraduate in Tongji University, and once made a superficial study on circular RNA. Now I am studying as a postgraduate in Professor Xiao-Ou Zhang 's lab, and I am trying to work on single-cell sequencing data. I am very interested in biology and machine learning, and you are welcome to communicate with me.

  • Mengyao Cui

    Mengyao Cui

    e-mail: 2311459@tongji.edu.cn

    Mengyao Cui received her B.S. in Applied Statistics from Northeastern University in 2023 and then joined Prof. Zhang's lab for her PhD. She is trying to engage in research that combines knowledge of mathematics and biology, and hopes to achieve some results.

  • Jing Yan

    Jing Yan

    e-mail: 2333161@tongji.edu.cn

    Jing Yan graduated from Huazhong Agricultural University in 2023 with a Bachelor's degree in Bioinformatics and subsequently joined Professor Zhang's laboratory to pursue a Master's degree. She is committed to exploring uncharted territories within biology and seeking innovative approaches to problem-solving. Continuously enhancing her research capabilities, she strives to achieve her scientific goals and professional ambitions.